精神分裂症应用利培酮治疗的远期疗效随访评价

Long Term Efficacy of Risperidone in the Treatment of Schizophrenia

目的探究精神分裂症应用利培酮治疗的远期疗效。方法选取60例精神分裂症患者作为观察对象,使用利培酮进行治疗,观察患者在治疗后3个月、12个月、24个月的长期治疗效果,并采用阴性和阳性症状评定量表(PANSS),评定患者的治疗效果,统计出现复发的情况。结果患者在治疗后3个月、12个月、24个月的治疗有效率为66.7%、68.0%、66.0%。3个月、12个月、24个月的复发率分别为16.7%、13.3%和13.8%。结论采用利培酮来治疗精神分裂症具有较好的效果,能够有效缓解患者的病情,且复发率较低,整体的恢复情况较为理想。

Objective To explore the long-term efficacy of risperidone in the treatment of schizophrenia. Methods Using risperidone for treatment, we selected 60 cases of patients with schizophrenia as observation objects.Then, after treatment for 3 months, 12 months and 24 months, we observed these patients＇ long-time effect. At last, using the negative and positive symptoms rating scale（PANSS） to assess the therapeutic effect on the patients and get a recurrence probability. Results After treatment for 3 months, 12 months and 24 months, these patients＇ treatment effective rate respectively were 66.7%, 68.3%, 68.3% and their recurrence rates were 16.7%, 13.3% and 13.8%. Conclusion Used to treat schizophrenia, risperidone has good effects which can effectively alleviate the patients, and make their recurrence rate low. The overall recovery is relatively ideal, which has the high medical significance.