探寻肥胖切点的方法在糖尿病筛查／诊断中的应用

The methods of exploring obesity cutoffs for screening/diagnosing diabetes

合适的肥胖切点（如BMI、腰围）有助于发现糖尿病及其高危人群，是实施肥胖干预的依据。由于种族差异，针对不同种族人群应制定不同的肥胖切点。目前肥胖切点的制定多使用受试者工作特征曲线，其他方法还有限制性立方样条和分式多项式模型。本文对应用以上3种方法寻找人群糖尿病筛查／诊断肥胖切点的研究现状进行综述，以期了解不同人群糖尿病筛查／诊断的肥胖切点、明确不同方法判定切点的意义。

It is important to establish an appropriate obesity-cutoff method to identify people with diabetes or at high risk of the disease. Aside from restricted cubic splines and fractional polynomial model, the receiver operating characteristic curve is the most frequently one used to define these cutoffs. In this study, we explored the obesity cutoffs across different ethnic populations and evaluated the merits/demerits of different Methods by reviewing the currently used obesity cutoffs.