牙周基础治疗联合局部药物治疗对糜烂型口腔扁平苔藓的临床效果观察

Clinical efficacy of basic periodontal therapy combined with local medication for erosive oral lichen planus

目的研究牙周基础治疗联合局部药物封闭对糜烂型口腔扁平苔藓患者的临床疗效。方法选取糜烂型口腔扁平苔藓伴慢性牙周炎患者56例,随机分为2组,试验组采用牙周基础治疗联合局部药物治疗,对照组仅采用局部药物治疗,观察治疗后1个月及6个月2组患者口腔扁平苔藓临床症状的改善。结果治疗后1个月试验组和对照组的有效率为92.86%和67.86%,试验组高于对照组（χ^2=5.54,P〈0.05）;治疗后6个月,试验组和对照组的有效率分别为85.71%和57.14%,试验组高于对照组（χ^2=5.60,P〈0.05）。结论牙周基础治疗有助于改善糜烂型口腔扁平苔藓患者的黏膜病损,提高疗效。

Objective To study the clinical efficacy of basic periodontal therapy combined with local medication for erosive oral lichen planus（ OLP）. Methods 56 patients with erosive oral lichen planus and periodontitis were randomly divided into two groups： experimental group and control group. Experimental group received basic periodontal therapy and drug therapy. Control group received drug therapy only. For all patients, the clinical symptoms of OLP were examined at baseline, one month after therapy and six month after therapy. Results One month after therapy, there was significant difference in the clinical effects of treatments between experimental group（ 92. 86%） and control group（ 67. 86%）（ P〈0. 05）. Six month after therapy, there was significant difference in the clinical effects of treatments between experimental group（ 85. 71%） and control group（ 57. 14%）（ P〈0. 05）. Conclusion Basic periodontal therapy can effectively relieve the clinical symptom of OLP in erosiveoral lichen planus patients with chronic periodontitis, indicating that periodontal intervention has positive therapeutic effect.