摘要
目的追踪随访深圳地区抗-HCV ELISA结果呈反应性、RIBA结果为不确定的献血者,研究分析其HCV转归情况,为抗-HCV ELISA呈反应性结果的无偿献血者召回提供理论基础和科学依据。方法追踪随访2年前32名抗-HCV RIBA结果为不确定的献血者,对其血液标本进行抗-HCV ELISA、HCV-RNA(NAT)、ALT以及HCV病毒载量检测,若HCV-RNA阴性则加做RIBA确证试验。结果 32例随访者血液标本中6例抗-HCV ELISA呈反应性,包含1例ALT升高同时HCV-RNA和病毒载量测定阳性;3例RIBA确证阳性。结论抗-HCV RIBA结果为不确定的献血者仍属于献血高危人群,存在一定的HCV输血传播风险。
Objective To provide theoretical and scientific basis for recalling the blood donors with reactive result of an- ti-HCV from ELISA and indeterminate result of anti-HCV from RIBA, to follow up and analyze their outcomes of HCV two yeats later. Methods 32 blood samples were collected in total, with all of them measured for anti-HCV by ELISA, HCV- RNA, ALT and HCV by viral load test. Anyone with negative result of HCV-RNA would be detected additionally by RIBA. Results Six cases had reactive results of anti-HCV from ELISA, including one case with abnormal result of ALT. Mean- while, that one case also had a positive result of HCV-RNA and viral load test. Three eases had positive results from RIBA. Conclusion There is a risk in blood transfusion from recalling the blood donors with indeterminate result of anti-HCV by RIBA.
出处
《中国输血杂志》
CAS
北大核心
2016年第2期168-170,共3页
Chinese Journal of Blood Transfusion