摘要
外周T细胞淋巴瘤(PTCL)为一组少见、高度异质性的淋巴系统恶性肿瘤,虽然PTCL发病率低于B细胞淋巴瘤,但其预后差。目前,PTCL缺乏标准一线治疗方案,PTCL患者长期生存率低。近年来,应用全新治疗组合方案进行的PTCL临床试验与新药的研究已初见成效。笔者拟就PTCL的治疗研究进展进行综述,旨在为临床工作提供参考。
Peripheral T-cell lymphoma (PTCL) is a group of rare and highly heterogeneous lymphoid malignancies. Although the incidence of PTCL is much lower than that of B-cell lymphoma, PTCL has a poorer prognosis. So far, no standard treatment has been established, which account for dismal long-term survival rate. In recent years, a number of novel agents and therapeutic regimens have shown promise in the treatment of PTCL. This review focuses on the new treatment progress of PTCL, in order to increase the reference for clinical work.
出处
《国际输血及血液学杂志》
CAS
2016年第2期158-163,共6页
International Journal of Blood Transfusion and Hematology
基金
国家自然科学基金项目(81372256)
浙江省科技厅公益性技术应用研究计划项目(2013C33125)
浙江省医药卫生科技计划项目(2012KYB078、2013KYB102)
关键词
淋巴瘤
T细胞
外周
药物疗法
药物批准
临床试验
Lymphomas, T-cell, peripheral
Drug therapy~ Drug approval~ Clinical trial