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41例血友病患者拔牙术的安全性研究

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摘要 目的观察血友病患者在给予标准替代治疗以及手术处理方案下拔牙术的安全性。方法拟进行拔牙术的血友病A和血友病B患者术前予单次凝血因子替代治疗(血浆因子水平目标值30%),并给予口服氨甲环酸至术后7日,同时采用标准的手术处理方案。结果共行拔牙50例次并拔除患牙58个,41例血友病患者中,12例患者术后次日因局部多量出血再次给予凝血因子输注,29例患者术后仅表现为创面少量渗血,未予特殊处理均自行血止。在为达到止血目的术后重复凝血因子输注的12例患者中,9例患者在术后次日给予预防输注等量的凝血因子替代治疗后未再有活动性出血;余3例患者因术后创面持续出血而予凝血因子连续输注3~5日后出血停止。结论血友病患者采用标准化围术期处理策略可安全地进行拔牙术。
出处 《中国临床医生杂志》 2016年第4期84-86,共3页 Chinese Journal For Clinicians
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参考文献12

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