右美托咪定辅助全身麻醉患者的镇静及全身麻醉药物的节俭作用

Dexmedetomidine patients given adjuvant systemic anesthesia sedation and general anesthesia drug effects thrifty

目的探究和分析使用右美托咪定辅助全身麻醉患者的镇静和使用麻醉药物的节俭作用。方法经数字表法随机选择2013年3月-2015年3月本院就诊全身麻醉患者100例,根据患者接受的辅助治疗方式均分成对照组和观察组两组。对照组使用浓度为0.9%的生理盐水联合丙泊酚辅助诱导麻醉,观察组使用右美托咪定联合丙泊酚辅助诱导麻醉。观察并比较两组麻醉的临床效果。结果对照组及观察组患者治疗前Ramsay镇静评分结果分别为(1.62±0.33)分、(1.63±0.31)分,差异无统计学意义(P>0.05),但治疗后两组Ramsay镇静评分分别为(1.93±0.24)分、(3.26±0.69)分,差异具统计学意义(P<0.05);观察组和对照组的丙泊酚用量分别为(36.67.±12.85)mg、(107.92.±44.44)mg,观察组用药量显著低于对照组,统计学上差异有意义(P<0.05)。结论使用右美托咪定能够实现良好的镇静和镇定作用,同时副作用较小,能够使得患者处于可配合治疗的状态,临床应用效果显著。

Objective To explore and analyze the use of dexmedetomidine in patients given adjuvant systemic anesthesia sedation and use of narcotic drugs frugal role. Methods The number table,randomly selected date 2013- March 2015 our hospital 100 patients under general anesthesia,according to patients receiving adjuvant treatment were divided into two groups control group and the observation group. The control group was 0. 9% saline concentration propofol induction of anesthesia assisted observation group using dexmedetomidine aid given propofol induction of anesthesia. The two groups were observed and compared the clinical effects of anesthesia. Results The control group and the observation group patients before treatment Ramsay sedation score results were（ 1. 62 ± 0. 33） points,（ 1. 63 ± 0. 31） points,the difference was not statistically significant（ P〉0. 05）,but the two groups after treatment Ramsay sedation scores were was（ 1. 93 ± 0. 24） points,（ 3. 26 ± 0. 69）points,a statistically significant difference（ P〈0. 05）; propofol observation group and control group were（ 36. 67 ±12. 85） mg,（ 107. 92 ± 44. 44） mg,the dosage of the observation group was significantly lower than the control group,the difference was statistically significant（ P〈0. 05）. Conclusion The use of dexmedetomidine sedative given to achieve a good and calming effect,while fewer side effects,can be made with the patient in a state can be treated,the clinical application of the effect is significant.