慢性肾脏病患儿激素药服用依从性的影响因素分析

Analysis on the Influencing Factors for Hormone Medication Compliance in Children with Chronic Kidney Disease

目的探讨慢性肾脏病(CKD)患儿激素药服用依从性及其影响因素,寻求相应的护理对策。方法 2013年5月-12月对96例CKD患儿在出院期间激素药服用状况进行调查,并对影响因素进行分析。结果激素药服用不依从者50例,占52%。主要监护人、父亲文化程度、母亲文化程度、居住地、病程、住院次数、治疗方案认知情况不同的患儿服药依从性间差异有统计学意义(P<0.05)。多因素logistic回归分析表明患儿病程[OR=2.204,95%CI(1.253,3.875),P=0.006]、居住地[OR=2.615,95%CI(1.023,6.687),P=0.045]、母亲文化程度[OR=0.147,95%CI(0.028,0.788),P=0.025]为影响患儿服药依从性的独立因素。结论 CKD患儿激素药服用依从性现状不容乐观,应积极采取有针对性的护理干预,提高患儿激素服药依从性,从而达到有效控制疾病和延缓疾病进展的目的。

Objective To explore the hormone medication compliance in children with chronic kidney disease（CKD） and analyze its inl uencing factors.Methods Between May and December 2013,96 children were investigated by questionnaires about medication compliance when they were out of the hospital.Then we analyzed the inl uencing factors for medication compliance.All the data were analyzed by SPSS 19.0 sot ware.Results Of these 96 children,medication nonadherence accounted for 52%（50）.The main guardian,educational level of the father,educational level of the mother,residence,duration of illness,time of hospitalization,and understanding of the treatment plan played signii cant roles in causing dif erent medication compliance among these children（P 〈0.05）.Logistic regression analysis showed that duration of illness [OR=2.204,95%CI（1.253,3.875）,P=0.006],residence [OR=2.615,95%CI（1.023,6.687）,P=0.045] and the mother＇s educational level [OR=0.147,95%CI（0.028,0.788）,P=0.025] were the independent factors for medication compliance.Conclusions According to the survey,hormone medication compliance in children with chronic kidney disease is not satisfying.We should strengthen the health education in children and their parents,and adopt specific interventions to enhance the medication compliance so as to ef ectively control the disease and delay the progression.