湖北省急性胃肠炎疾病人群负担评估

Disease burden of acute gastrointestinal illness in Hubei province: a population-based estimation

目的评估湖北省人群急性胃肠炎疾病负担。方法采用多阶段整群随机抽样的方法抽取调查对象,2012年1—12月每月入户问卷调查其急性胃肠炎发生和就诊情况。结果共调查3 891人,急性胃肠炎月患病率为4.1%（95%CI=3.4%~4.7%）,年发病概率为41.7%（95%CI=36.2%~46.6%）,年发病率为0.49（95%CI=0.42~0.57）次/人年。按人口结构加权,加权月患病率为4.9%（95%CI=4.2%~5.6%）,加权年发病概率为47.8%（95%CI=42.8%~52.8%）,加权年发病率为0.65（95%CI=0.56~0.74）次/人年。由此推算,湖北省2012年共有3756.4万人次感染急性胃肠炎,因病就诊2 434.1万人次,因病住院296.8万人次。结论湖北省人群2012年急性胃肠炎疾病负担较重,政府应予以关注和重视。

Objective To estimate the disease burden of acute gastroenteritis in the population of Hubei province.Methods M ulti-stage random cluster sampling was used to recruit participants for the study. Household interviews were conducted from January through December 2012 to collect information on the incidence and treatment of acute gastroenteritis among the participants. Results Totally 3 891 people were surveyed. The observed monthly prevalence of acute gastroenteritis was 4. 1%（ 95% confidence interval[95% CI ]： 3. 4%- 4. 7%）; the annual incidence probability was41. 7%（ 95% CI： 36. 2%- 46. 6%）; and the annual incidence rate was 0. 49（ 95% CI： 0. 42- 0. 57） episodes per personyear. Weighted by population size,the adjusted monthly prevalence was 4. 9%（ 95% CI： 4. 2%- 5. 6%） and the annual incidence probability was 47. 8%（ 95% CI： 42. 8%- 52. 8%）,with an annual incidence rate of 0. 65（ 95% CI： 0. 56-0. 74） episodes per person-year. The estimated person-times of acute gastroenteritis incident were 37. 564 millions in Hubei in 2012,with 24. 341 millions person-times of clinic visit and 2. 968 millions person-times of hospitalization. Conclusion The disease burden of acute gastroenteritis was heavy in Hubei province in 2012. The government agencies should pay attentions to the problem.