难治性肠易激综合征患者的生活质量及其影响因素被引量：2

Quality of life and its risk factors in refractory irritable bowel syndrome patients

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摘要目的探讨难治性肠易激综合征(RIBS)患者的生活质量及影响因素。方法采用症状严重程度量表(IBS-SSS)、汉密尔顿焦虑/抑郁量表(HAMA/HAMD)和生活质量量表(IBS-QOL)对601例消化专科门诊连续IBS患者和同期匹配的100例健康体检者进行测评,并通过多重线性回归分析探讨RIBS患者生活质量的影响因素。结果 RIBS组IBS-QOL总评分及IBS-QOL8个维度评分低于非RIBS组和健康对照组(P<0.05)。RIBS不同亚型间的IBS-QOL总评分无统计学意义(P>0.05),但在冲突行为、健康忧虑、社会反映3个维度方面有统计学意义(P<0.05)。IBS-SSS症状评分和焦虑症状评分为RIBS患者生活质量的影响因素。结论难治性IBS患者的生活质量差,临床症状和焦虑情绪为其重要影响因素。 Objective To explore quality of life and its risk factors in patients with refractory irritable bowel syndrome（ RIBS）. Methods 601 IBS patients in gastroenterology clinic and 100 healthy volunteers were invited to complete irritable bowel syndrome- symptom severity scale（ IBS-SSS）,the Hamilton Rating Scale of Anxiety / Depression（ HAMA / HAMD）,Irritable bowel syndrome-quality of life（ IBS-QOL）. And multiple linear regression analysis was used to explore the determinants of quality of life in patients with RIBS. Results The overall score and subscale scores of IBS-QOL in RIBS group were lower than those in the non-RIBS and healthy group（ P〈0. 05）. There were no significant differences in the overall scores of IBS-QOL among different subtypes of RIBS. However,the interference with activities,health anxious,social reaction scores were different among the subtypes（ P〈0. 05）. Multiple linear regression analysis demonstrated that quality of life in RIBS was independently associated with the scores in IBS-SSS and HAMA. Conclusion Quality of life in RIBS is obviously decreased. Quality of life in RIBS is closely related to clinical symptoms and anxiety condition.

作者黄伟泉刘静贾林刘彬彬江舒曼许鸣王胜炳

机构地区广州市南沙区南沙街社区卫生服务中心广州市第一人民医院南沙医院消化内科广东省第二人民医院消化内科梅州市人民医院消化内科

出处《广州医药》 2016年第2期63-66,共4页 Guangzhou Medical Journal

关键词难治性肠易激综合征生活质量 Refractory Irritable bowel syndrome Quality of life

分类号 R574 [医药卫生—消化系统]

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参考文献9

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