细胞因子在肺动脉高压发病中作用的研究进展

Research progress of cytokines in the pathogenesis of pulmonary hypertension

肺动脉高压是一类发病率低,但常引起右心衰竭等最终导致患者死亡的严重肺血管疾病,其形成的主要病理改变是肺血管重构和肺血管收缩,多种细胞因子异常作用参与发病,对该作用机制的研究成为了治疗疾病,改善疾病预后的关键。

Pulmonary hypertension is a kind of low incidence,but it is often caused by right heart failure and other serious pulmonary vascular disease. The main pathological changes of pulmonary vascular include remodeling and pulmonary vascular contraction,and many kinds of cytokines are involved in the pathogenesis of disease,which is the key to improve the prognosis of the disease.