运用两种心理学量表评估老年病人术后早期认知功能的比较研究被引量：2

COMPARATIVE STUDY ON EVALUATION OF EARLY POSTOPERATIVE COGNITIVE FUNCTION OF ELDERLY PATIENTS WITH TWO KINDS PSYCHOLOGICAL SCALES

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摘要目的:观察应用MMSE量表和Mo CA量表评估老年病人全麻术后的早期认知功能。方法:老年全麻手术病人66例,分别于术前1d和术后3h、6h、24h、48h应用MMSE量表和Mo CA量表评估病人的认知功能。结果:病人术后3h、6h的MMSE、Mo CA测试评分最低;术后各时间点的Mo CA评分均明显低于MMSE评分(P<0.05)。MMSE量表显示18.18%(12例)的病人术后出现认知功能障碍,Mo CA量表显示25.76%(17例)的病人出现认知功能障碍,两种量表评估病人认知障碍发生率比较差异无统计学意义(P>0.05)。结论:Mo CA量表可作为评估老年病人全麻术后早期认知功能障碍的首选;MMSE和Mo CA两种量表共同评估或Mo CA量表较MMSE更适于评估老年病人术后早期的认知功能。 Objective： To evaluate the early postoperative cognitive function of elderly patients after general anaesthesia operation using MMSE scale and Mo CA scale. Methods： MMSE scale and Mo CA scale were used to evaluate the cognitive function of 66 cases elderly general anaesthesia operation patients 1d before operation, 3h, 6h, 24 h, 48 h after operation respectively. Results： The MMSE score and Mo CA score 3h, 6h after operation were the lowest; The Mo CA score at each time point after operation were obviously lower than MMSE score（P〈0.05）. MMSE scale and Mo CA scale respectively showed that 18.18%（12/66） and 25.76%（17/66） patients suffered cognitive dysfunction after operation; but there had no statistical signifi cance about incidence of cognitive dysfunction between 2 scales（P〉0.05）. Conclusions： Mo CA can be acted as fi rst choice for evaluating early postoperative cognitive dysfunction of elderly patients after general anaesthesia operation. Compared with MMSE scale, it is more suitable for using Mo CA scale or Mo CA scale combined MMSE scale to evaluate the early postoperative cognitive function of elderly patients.

作者李艳刘玉伶曹雪峰王俊华乔丽

机构地区承德医学院附属医院麻醉科

出处《承德医学院学报》 2016年第3期192-194,共3页 Journal of Chengde Medical University

关键词 Mo CA量表 MMSE量表老年病人术后早期认知功能障碍 Mo CA scale MMSE scale Elderly patients Early postoperative cognitive dysfunction

分类号 R614.2 [医药卫生—麻醉学]

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参考文献8

1Kasten M, Bruggemann N, Schmidt A, et al. Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease[J]. Neurology, 2010, 75(5): 478.
2Dalrvmple-Alford JC, MacAskill MR, NAkas CT, et al. The MoCA: well-suited screen for cognitive impairment in Parkinson disease[J]. Neurology, 2010, 75(19): 1717-1725.
3姜美娟,陶华英.蒙特利尔认知评估量表用于血管源性轻度认知功能障碍评估的初步研究[J].山东医药,2011,51(12):40-42. 被引量：11
4韩学昌,邢群智.氟马西尼用于全凭静脉麻醉术后催醒的临床研究[J].当代医学,2012,18(12):148-150. 被引量：10
5王强,王成才.异氟醚诱发POCD的研究现状及p38MAPK通路的调控[J].山东医药,2010,50(51):117-118. 被引量：4
6Dijkstra JB, Houx PJ, JoUes J. Cognition after major surgery in the elderly: test performance and complaints[J]. Br J Anaesth, 1999,82(6): 867-874.
7Moiler JT, Cluitmans P, Rasmussen LS, et al. Long-term postoperative cognitive dysfunction in the elderly ISPOCD 1 study. IS-POCD investigators. International Study of Post-Operative Cognitive Dysfunction[J]. Lancet, 1998, 351(9106): 857-861.
8白晶,李宝栋,韩璎.蒙特利尔认知评估量表在不同地区应用现状[J].华西医学,2012,27(4):637-640. 被引量：5

二级参考文献45

1袁辉,杨胜,周文霞,张永祥.MAPK级联信号通路与长时程增强[J].中国药理学通报,2006,22(7):769-774. 被引量：38
2Crosby C,Culley DJ,Baxter MG.Spatial memory performance 2 weeks after general anesthesia in adult rats[J].Anesth Analg,2005,101(5):1389-1392.
3Yang H,Liang G,Hawkins BJ.Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies[J].Anesthesiology,2008,109(2):243-250.
4Tas PW,Eisemann C,Roewer N.The volatile anesthetic isoflurane suppresse spontaneous ca lcium oscillations in vitor in rat hippocarnpal neurons by activation of adenosine A1 receptors[J].Neuorsci Lett,2003,338(3):229-232.
5Zheng S,Zuo Z.Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebelar slices[J].Brain Res,2005,1054(2):143-151.
6Moe MC,Berg JJ,Larsen GA,et al.The effect of isoflurane and sevoflurane on cerebrocortical presynaptic Ca2+ and protein kinase C activity[J].J Neurosurg Anesthediol,2003,15 (3):209-214.
7Cirillo PF,Pargellis C,Regan J.The non-diaryl heterocycle classes of p38 MAP kinase inhibitors[J].Curt Top Med Chem,2002,2(9):1021-1035.
8Lee MR,Dominguez C.MAP Kinase p38 inhibitors:Clinical results and an intimate look at their interactions with p38alpha protein[J].Curt Med Chem,2005,12(25):2979-2994.
9Neuropathology Group. Medical Research Council Cognitive Function and Aging Study. Pathological correlates of late-onset dementia in a muhicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) [ J]. Lancet, 2001,357 ( 9251 ) : 169-175.
10Nazem S, Siderowf AD, Duda JE, et al. Montreal cognitive assessment performance in patients with Parkinson's disease with " normal" global cognition according to mini-mental state examination score [J]. J Am Geriatr Soc, 2009,57(2) :304-308.