胰腺癌与新发2型糖尿病的关系

RELATIONSHIPS BETWEEN PANCREATIC CARCINOMA AND NEW TYPE 2 DIABETES MELLITUS

目的:探讨胰腺癌与新发2型糖尿病之间的关系。方法:以89例胰腺癌患者为胰腺癌组,以同期非肿瘤、非消化系统、非激素代谢异常相关疾病的123例患者作为对照组,分析比较胰腺癌组与对照组患者糖尿病的发病率和病程。结果:89例胰腺癌患者合并糖尿病者36例(40.44%),明显高于对照组糖尿病的发病率(24.39%,P<0.05)。89例胰腺癌患者中,32.58%(29/89)糖尿病病程在2年以内,明显高于对照组(12.19%,P<0.05);两组糖尿病病史两年以上患者比例比较,差异无统计学意义(P>0.05)。结论:糖尿病可能是胰腺癌的早期临床表现;对于近2年内诊断的老年糖尿病患者或血糖短时间出现较大波动的老年患者,需警惕胰腺癌的可能。

Objective： To explore the relationships between pancreatic carcinoma and new type 2 diabetes mellitus. Methods： 89 pancreatic carcinoma patients were taken as pancreatic carcinoma group; 123 cases non-tumour, non-alimentary system and non-metabolic abnormality patients were taken as control group at the same time. The incidence and course of diabetes mellitus of pancreatic carcinoma group and control group were analyzed and compared. Results： The incidence of diabetes mellitus of pancreatic carcinoma group was 40.44%（36/89）, which was obviously higher than that of control group（24.39%, P〈0.05）. In pancreatic carcinoma group, the diabetes mellitus course of 32.58%（29/89） patients was within 2 years, which was obviously higher than control group（12.19%, P〈0.05）; But there had no statistical difference in the proportion of patients with diabetes mellitus for more than 2 years（P〉0.05）. Conclusions： Diabetes mellitus may be an early clinical manifestation of pancreatic carcinoma. Clinicians should to be alert to the possibility of pancreatic carcinoma for elderly patients in diagnosis of diabetes mellitus in 2 years or blood glucose fl uctuation great in short time.