淋巴结转移对胸段食管鳞癌患者预后的影响

The influence of lymph nodes metastasis on the prognosis of patients with thoracic esophageal squamous cell carcinoma

目的：探讨淋巴结转移数量、转移度及转移区域数对胸段食管鳞癌患者预后的影响。方法：回顾性分析我科根治性切除的56例胸段食管鳞癌患者的区域淋巴结转移情况临床资料,应用：Kaplan-Meier法进行术后生存分析,组间比较用log-rank检验。结果：有淋巴结转移者的术后生存率低于无淋巴结转移者;随着淋巴结转移数量、转移度及转移区域数的增加,患者的术后生存率逐渐降低。当淋巴结转移数量达到3-5枚、转移度〉10%及转移区域数达到2个时,提示患者食管癌预后不良。结论：淋巴结转移数量、转移度及转移区域数均可作为判断食管癌预后的良好指标。

Objective：To investigate the effect of the number of lymph node metastasis,the ratio of lymph node metastasis and the number of metastatic regions on the prognosis of patients with thoracic esophageal squamous cell carcinoma.Methods：A retrospective study was made on the clinical data of regional lymph node metastasis for 56 patients with thoracic esophageal squamous carcinoma who underwent radical esophagectomy.The survival analysis was performed by Kaplan-Meier method after the operation,and the log-rank test was used to compare the groups.Results：The postoperative survival rate of patients with lymph node metastasis was lower than those without lymph node metastasis.With the increase of the number of lymph node metastasis,the ratio of lymph node metastasis and the number of metastatic regions,the postoperative survival rate of patients was gradually decreased.It was more reminder of a poor prognosis when the number of lymph node metastasis reached 3-5,the ratio of lymph node metastasis was more than 10%and the number of metastatic regions reached 2.Conclusion：The number of lymph node metastasis,the ratio of lymph node metastasis and the number of metastatic regions can be used as good indicators to evaluate the prognosis of esophageal carcinoma.