心力衰竭患者睡眠呼吸暂停的调查

Study on obstructive sleep apnea in patients with heart failure

目的:分析心力衰竭患者睡眠呼吸暂停(SA)的发生率,评估此类人群SA发生的危险因素。方法:对486例于心脏内科住院的心力衰竭患者进行柏林问卷调查,分为SA高危组和SA低危组。测量颈围、腹围、身高、体重,计算体重指数。进行相关数据统计分析。结果:所有患者中,SA高危组153例,占31.5%。SA高危组患者的颈围、腹围以及高血压、糖尿病、高脂血症、慢性肾功能不全、吸烟、饮酒、既往脑血管意外、BMI>30kg/m^2的比率均明显高于SA低危组(P<0.05),而男女之间无明显差异。多因素logistic回归分析显示,高血压、饮酒、既往脑血管意外、颈围、体重指数与SA的发生相关(P<0.05)。结论:心力衰竭患者高危SA的发生率高于普通人群,男女之间无明显差异。此类人群SA发生的危险因素与普通人群相似。

Objective：To investigate the prevalence of sleep apnea（SA） in patients with heart failure and explore the risk factors of SA in such patients.Methods：According to berlin questionnaire,486 patients with heart failure hospitalized in cardiology department were divided into SA high risk and SA low risk.Patients＇ neck circumference,abdominal circumference,height,and weight were measured,and body mass index（BMI） was calculated.Results：Among the total patients,153（31.5%） were SA high risk.Neck circumference,abdominal circumference and BMI were significantly higher in SA high risk group than those in SA low risk group（P〈0.05）.Patients with SA high risk were more likely to have hypertension,diabetes,hyperlipidemia,chronic renal dysfunction,smoking,alcohol consumption,previous cerebrovascular accident and obesity（P〈0.05）.However,we have not found the gender difference of SA in this cohort.Multiple logistic regression analysis revealed that hypertension,alcohol consumption,previous cerebrovascular accident,neck circumference and BMI remained predictors of SA after adjusting for other confounders（P〈0.05）.Conclusions：SA high risk was higher prevalence in patients with heart failure,and the gender difference on the prevalence of SA high risk was not significant in such patients.Patients with heart failure and general population had the similar risk factors.