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男性2型糖尿病患者骨密度变化及其相关因素探讨 被引量:3

Discussion on the Changes and Related Factors of Bone Mineral Density of Male 2-Type Diabetes Mellitus
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摘要 目的探讨男性2型糖尿病(DM)患者骨密度(BMD)变化情况及其相关因素。方法选取2014年1月至2015年10月来我院就诊的男性2型DM患者100例,根据是否合并骨质疏松(OP)分为实验组(合并OP)和对照组(未合并OP)各50例。比较两组患者身体不同部位的BMD以及生化指标水平。结果实验组L_1、L_2、L_3、L_4、L_(1-4)、Neck、Ward三角、大转子以及股骨全部部位的BMD均显著低于对照组,差异有统计学意义(P<0.05)。两组患者FBG、HBA1c无统计学差异(P>0.05),实验组血清Ca、血睾酮(T)明显低于对照组,而血清P、碱性磷酸酶(ALP)明显高于对照组(P<0.05)。结论男性2型糖尿病合并OP患者全身各个部位的骨量均有所下降,而血清Ca、P、T、ALP对患者BMD变化的影响较大。 Objective To discuss the changes of bone mineral density (BMD) and its related factors of male 2-type diabetes mellitus (DM). Methods 100 male patients with 2-type DM treated in our hospital from January 2014 to October 2015 were selected and divided into experimental group (with osteoporosis) and control group (without osteoporosis) according to whether complicating osteoporosis, with 50 cases in each group. The BMD in different parts of the body and biochemical indices of two groups were compared, Results The BMD in L1, L2, L3, L4, L1-4, Neck, Ward triangle, greater trochanter and all parts of the femur of experimental group were significantly lower than those of control group (P〈0.05). The levels of FBG and HBAlc of two groups had no statistical difference (P〉0.05); the levels of serum Ca and testosterone (T) of experimental group were lower than those of control group, and the levels of serum P and alkaline phosphatase (ALP) of experimental group were higher than those of control group (P 〈0.05). Conclusions The bone mass in the entire body of male patients with 2-type diabetes mellitus complicating osteoporosis decreases significantly. Serum Ca, P, T and ALP have great influence on the changes of bone mineral density.
出处 《临床医学工程》 2016年第4期443-444,共2页 Clinical Medicine & Engineering
基金 广东省清远市科技计划项目医疗卫生领域自筹经费项目"2型糖尿病男性患者骨密度变化分析及影响因素研究"(项目编号:2014B156)
关键词 2型糖尿病 男性 骨密度 2-type diabetes mellitus Male Bone mineral density
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