氟哌啶醇结合心理行为疗法治疗儿童抽动障碍疗效观察

Effect Observation of Haloperidol Combined with Psychological Behavioral Therapy in Treatment of Children with Tic Disorders

目的探讨氟哌啶醇结合心理行为疗法治疗儿童抽动障碍的疗效。方法将2013年1月至2014年12月来我院诊治的70例儿童抽动障碍患者随机分成观察组和对照组,每组各35例。对照组采用常规氟哌啶醇治疗,观察组采取氟哌啶醇结合心理行为疗法治疗。使用抽动问卷评价临床疗效差异。结果两组治疗后抽动问卷调查各因子(发声性抽动、运动性抽动、行为、运动不宁)评分较治疗前均显著降低,且观察组治疗后抽动问卷各因子评分显著低于对照组,差异均具有统计学意义(P<0.05)。观察组治疗后临床总有效率为97.14%,明显高于对照组的80.0%,差异具有统计学意义(P<0.05)。结论氟哌啶醇结合心理行为疗法治疗可显著改善儿童抽动症状,且治疗效果显著优于常规氟哌啶醇治疗。

Objective To investigate the clinical effects of hatoperidol combined with psychological behavioral therapy in the treatment of children with tic disorders （TD）. Methods 70 children with tic disorders treated in our hospital from January 2013 to December 2014 were selected and randomly divided into observation group and control group, with 35 cases in each group. The control group was given conventional haloperidol therapy, the observation group was given haloperidol combined with psychological behavioral therapy. The clinical efficacy was evaluated by Tic evaluation questionnaire. Results After the treatment, the Tic questionnaire scores of vocal tic, motor tic, behavior, motor restlessness in two groups increased significantly, and the scores of observation group were significantly lower than those of control group, with statistically significant difference （P 〈0.05）. The total effective rate of observation group was 97.14%, significantly higher than 80.00% of control group, with statistically significant difference （P〈O.05）. Conclusions Haloperidol combined with psychological behavioral therapy can significantly improve the tic symptoms of children, and has better curative effects than conventional haloperidol therapy.