摘要
烟雾病是一种进行性脑血管闭塞性疾病,以脑底异常血管网形成为特征,是引起儿童和成人卒中的一个重要原因。烟雾病的病因目前尚不明确,本文将从遗传、血管生成以及免疫炎症3个方面对其发病机制进行综述。
Moyamoya disease is a progressive cerebrovascular occlusive disease, which is characterized by the formation of abnormal vascular network at the brain base. It is an important cause of stroke in children and adults. Now, the etiology of moyamoya disease is not clear. This article reviews its pathogenesis from 3 aspects, including genetic factors, angiogenesis, and immune inflammation.
出处
《国际脑血管病杂志》
2016年第2期142-145,共4页
International Journal of Cerebrovascular Diseases
基金
国家自然基金重点项目(81230026)
江苏省领军人才和创新团队项目(LJ201101)
关键词
烟雾病
新生血管化
病理性
内皮祖细胞
血管内皮生长因子A
成纤维细胞生长因
子2
转化生长因子β
肝细胞生长因子
自身免疫疾病
炎症
Moyamoya Disease
Neovasculafization, Pathologic
Endothelial Progenitor Cells
VascularEndothelial Growth Factor A
Fibroblast Growth Factor 2
Transforming Growth Factor β
Hepatocyte GrowthFactor
Autoimmune Diseases
Inflammation