不同年龄男性人群代谢综合征的特点分析

Characteristics of metabolic syndrome in male group at different age stages

目的 探讨不同年龄段男性人群代谢综合征特点,为其防治提供依据。方法 回顾性分析北京某机关677例男性干部2007年5月在我院查体资料,按年龄分为4组：33~45岁、46~55岁、56~65岁和〉65岁,统计各组患病情况及相关异常代谢指标,分析不同年龄组上述指标特点。结果 677例健康体检干部中代谢综合征（MS）总患病率为23.78%,MS主要组成部分患病率从高到低为餐后2 h血糖增高（37.67%）、超重（37.08%）、高三酰甘油血症（31.17%）、高血压（18.02%）、低HDL-C血症（14.18%）、空腹血糖增高（11.37%）;各组MS发病率均较高,以46~55岁年龄组最高（31.87%）,33~45岁年龄组最低（17.53%）,56~65岁年龄组与〉65岁年龄组患病率相近（P〉0.05）。各年龄段中,33~45岁年龄组与56~65岁年龄组患病率最高的单项代谢异常疾病为超重（分别为32.47%和38.42%）,46~55岁年龄组最高为高三酰甘油血症（46.15%）,而〉65岁年龄组为餐后2 h血糖增高（57.93%）。结论 该机关人群MS患病率较高,46~55岁为其高发年龄段,超重及高三酰甘油血症为该人群MS早期主要危险因素,血糖紊乱及高血压为MS晚期主要临床表现,因此应加强干部人群的健康管理,有效预防MS及心脑血管疾病。

Objective To discuss the characteristics of metabolic syndrome （MS） in male group at different age stages, and provide the evidence for prevention and treatment of MS. Methods The materials of 677 male officials with health examinations were retrospectively analyzed on May 2007, and divided, according to age, into 33-45 group, 46-55 group, 56-65 group and 〉65 group. The MS status and relevant indexes of MS were observed and characteristics of all indexes were analyzed in all groups. Results The total prevalence of MS was 23.78% in 677 male officials. The prevalence of elevated 2-hour postprandial blood glucose was 37.67%, overweight was 37.08%, hypertriglyeeridemia was 31.17%, hypertension was 18.02%, low high-density lipoprotein cholesterol was 14.18%, and high fasting blood glucose was 11.37%. The incidence of MS was higher in all groups, and was the highest in 46-55 group （31.87%） and lowest in 33-45 group （17.53%）. The incidence of MS was similar in 56-65 group and 〉65 group （P〉0.05）. The prevalence of overweight was the highest in 33-45 group （32.47%） and 56-65 group （38.42%）, that of hypertriglyeeridemia was the highest in 46-55 group （46.15%）, and that of elevated 2-hour postprandial blood glucose was the highest in 〉65 group （57.93%）. Conclusion The prevalenee of MS is higher in the male group in this study. The risk age range is from 46 to 55, and overweight and hypertriglyceridemia are major risk factors of early MS. Dysglycemia and hypertension are main symptoms of late MS. Health management should be strengthened to help officials to prevent MS and cardiovascular and cerebrovascular diseases effectively.