不同药物预防根管治疗期间急症的临床效果

Effect of different drugs in prevention of inter-appointment emergencies

目的探讨根管治疗期间使用不同根管消毒药物对预防根管治疗期间急症（inter-appointment emergencies,IAE）的临床效果。方法选择2015年1月~2015年12月山西省中西医结合医院牙体牙髓科行根管治疗及再治疗的患者98例,根据用药不同将其随机分为3组,戊二醛组,氢氧化钙组以及奥硝唑-地塞米松组。比较分析各组预防IAE有效率及急性发作指数（flare-up index,FUI）。结果戊二醛组,氢氧化钙组及奥硝唑-地塞米松组预防IAE的有效率分别为63.64%,78.13%和84.85%,奥硝唑-地塞米松组预防IAE的有效率显著高于戊二醛组（χ^2=5.280,P〈0.05）,但与氢氧化钙组比较差异无统计学意义（χ^2=1.100,P〉0.05）。FUI指数比较：戊二醛组（3.65±1.21）〉氢氧化钙组（2.37±0.65）〉奥硝唑-地塞米松组（1.44±0.57）。结论奥硝唑-地塞米松预防IAE的效果较好,可以降低IAE的疼痛程度。

Objective To investigate the effect of different Shan＇xi Hospital of Integrated Traditional Chinese and Western Medicine root canal sterilized medicine on inter-appointment emergencies（ IAE）. Methods A total of 98 patients with root canal therapy or retreatment from January 2015 to December 2015 in were selected,according to the different therapy,the patients were randomly divided into glutaraldehyde group,calcium hydroxide group and ornidazole-dexamethasone group. The effective rate of IAE prevention and flare-up index（ FUI） were observe and compared. Results The effective rate of IAE prevention of glutaraldehyde group,calcium hydroxide group and ornidazole-dexamethasone group were 63. 64%,78. 13% and84. 85%,the IAE prevention of ornidazole-dexamethasone group was better than that of glutaraldehyde group（ χ2= 5. 280,P〈0. 05） while has no significant difference compared with calcium hydroxide group（ χ2= 1. 100,P〉0. 05）. Flare-up index（ FUI） results showed,glutaraldehyde（ 3. 65 ±1. 21） 〉calcium hydroxide group（ 2. 37 ± 0. 65）〉 ornidazole-dexamethasone group（ 1. 44 ± 0. 57）. Conclusion Ornidazole-dexamethasone has the best preventive effect of IAE,which could reduce the pain degree.