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秀丽隐杆线虫调节渗透平衡机制的研究进展 被引量:1

Research Progress on Osmotic Balance Regulation Mechanism of Caenorhabditis Elegans
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摘要 维持生物体内渗透压平衡对生物生长发育十分重要。秀丽隐杆线虫(Caenorhabditis elegans)被广泛用于研究生物在不利环境的抗性机制;同时,由于其进化的保守性,可为研究高等生物的体内渗透压调节提供参考。对秀丽隐杆线虫感知体外渗透压的相关基因和组织进行了介绍,分析了秀丽隐杆线虫调节体积的相关通路,综述了维持蛋白质稳态对渗透压的调节作用。 It is very important for the growth and development of organism to maintain osmotic pressure balance in vivo.Caenorhabditis elegans is widely used for the research of resistance mechanism under adverse environmental conditions.In the meantime,the conservation of its evolution provides reference for the study of osmotic pressure regulation in vivo of higher organisms.In this paper,the relative genes and tissues of osmotic pressure regulation in vitro in Caenorhabditis elegans are introduced,the relative pathways of volumn regulation in Caenorhabditis elegans are analyzed,and the effects of maintain protein homeostasis on osmotic pressure regulation are reviewed.
出处 《化学与生物工程》 CAS 2016年第4期4-8,共5页 Chemistry & Bioengineering
关键词 秀丽隐杆线虫 渗透平衡 TRP通路 WNK/GCK-Ⅶ信号通路 蛋白质稳态 Caenorhabditis elegans osmotic balance TRP channel WNK/GCK-Ⅶ signal channel protein homeostasis
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