益生菌制剂治疗130例新生儿抗生素诱发性腹泻临床观察

Clinical observation of probiotic therapy on 130 neonatal children antibiotic associated diarrhea

目的探讨不同益生菌制剂在新生儿抗生素诱发性腹泻中的治疗效果。方法选取我院因新生儿呼吸道、肺部、脐带感染住院的130例患儿作为研究对象,A组65例口服三联双歧杆菌胶囊,B组65例口服双歧杆菌胶囊。比较2组抗生素相关性腹泻治愈时间及治愈率。结果 A组腹泻治愈时间短于B组,治愈率高于B组,差异均有统计学意义(P<0.05)。结论三联双歧杆菌胶囊治疗新生儿抗生素相关性腹泻的效果更好,值得推广。

Objective The purpose of this paper is to find a better probiotic preparation for antibiotic associated diarrhea of neonatal children. Method 130 neonatal children who were affected by respiratory tract infection,pneumonia and umbilical cord inflammation were divided into 2 groups. Group A and B were given oral Bifid-triple viable capsule and Live Bifidobacterium capsules separately. The time and rate of recovery were compared between 2 groups. Result The time and rate of recovery in Group A were higher than those in Group B with a statistics significance（P0.05）.Conclusion Bifid-triple viable capsule were more efficient than Live Bifidobacterium capsules in reducing of antibiotic associated diarrhea of neonatal children.