频率域光声成像系统的研究

Frequency-domain photoacoustic imaging system

频率域光声成像是指使用连续波激光器输出激光光源,利用该调制后的激光信号辐射组织,在频率域对激励的光声信号进行处理并成像的方式。首先阐述光声成像和频率域光声成像的原理、发展以及研究现状,然后介绍频率域光声成像的具体实验方法和基本重建算法。为了弥补时域光声成像成本高、伤害性大、便携性差等缺点,提出了频率域光声成像的两种成像方式,给出了完整的实验系统结构图,展示其相对于传统时域光声成像不同的研究特点与方向。最后对频率域光声成像进行展望,为光声成像在国内的研究和发展提供一定的借鉴和引导。

Frequency-domain photoacoustic imaging is a new imaging modality, which uses the output amplitude information periodically modulated by a continuous-wave laser as a light source to stimulate biological tissues and to produce photoacoustic signals processed at frequency-domain and used to image the tissues. Firstly, the principles, developments and research status of photoacoustic imaging and frequency-domain photoacoustic imaging were introduced, and then the specific test methods and basic reconstruction algorithms of the frequency-domain photoacoustic imaging filed were described. In order to make up for time domain photoacoustic imaging with high costs, great harmful, poor portability and so on shortcomings, two imaging modalities were proposed and two complete experimental system structure diagrams were exhibited, showing different features and developing directions of photoacoustic imaging with respect to the traditional domain-photoacoustic imaging. At last, the outlook of the frequency-domain photoacoustic imaging was made to provide some references and guidance for our research and development about photoacoustic imaging.