食管良性狭窄内镜下治疗的研究进展

Progress of Endoscopic Treatment for Benign Esophageal Strictures

食管良性狭窄由多种原因引起,以吞咽困难为主要临床表现,严重影响患者的生活质量。大多数食管良性狭窄可以通过约3次内镜下扩张达到长期缓解,但仍有一部分难治性食管良性狭窄需要通过内镜置入支架或局部注射药物治疗,这些治疗方式短期内疗效较为肯定,但中长期的疗效不佳,往往需要再次干预。近年来,生物降解支架以及药物洗脱支架也在不断尝试,取得了很好的疗效。本文对治疗食管良性狭窄的方法作一综述。

Benign esophageal strictures can arise from various causes and mainly induce dysphagia. Commonly,the majority of benign esophageal strictures can achieve long-term relief through about three dilation sessions. However,some refractory benign esophageal strictures require other treatments,such as endoscopic stent placement and intralesional drug injection,but these treatments just attain short-time satisfactory results with a disappointingly low rate of long-term improvement. Recently,biodegradable stents and drug-eluting stents are developing and have obtained the positive effects. In this paper,we performed a review about the treatment of benign esophageal strictures.