抗氨基甲酰化蛋白抗体的临床应用

Clinical application of anti-carbamylated protein antibody

类风湿关节炎(rheumatoid arthritis,RA)是一种常见的,以关节慢性炎症性病变为主要临床表现的自身免疫病。抗氨基甲酰化蛋白(carbamylated proteins,Car P)抗体作为一种新发现的自身抗体指标在RA诊断、RA疾病前期筛查中具有潜在的研究价值和重要的应用前景。文中就抗Car P抗体在RA以及相关自身免疫病中的研究进展做一综述,以期为临床相关疾病的诊断及治疗提供新的研究方向。

Rheumatoid arthritis（ RA） was a common autoimmune disease characterized with main clinical manifestations of chronic inflammation in joints. Anti-carbamylated proteins（ anti-Car P） antibody,as a promising bio-marker,played a crucial role in the diagnosis of RA patients and the screening of pre-RA patients. In this article,recent progress on the study of anti-Car P antibody and RA related diseases has been reviewed,which was expected to provide new references for the diagnosis and treatment of related clinical diseases.