临床药师参与会诊颅内感染患者遴选抗菌药物的体会

Experience of clinical pharmacist participating in the selection of antimicrobial agents for consultation in patients with intracranial infection

目的探讨临床药师参与会诊颅内感染患者遴选抗菌药物的效果。方法本院于2015年9月29日收治1例疑似颅内感染患者,经临床药师参与会诊和遴选抗菌药,入院后治疗药物由头孢哌酮舒巴坦调整为替加环素。抗感染治疗5 d后,综合评估患者状况,临床药师建议停用替加环素,继续给予头孢唑肟降阶梯治疗。结果经有效的抗菌治疗后,患者血常规、红细胞沉降率、降钙素原(PCT)、C反应蛋白(CRP)炎性指标较前好转,咳嗽、咳痰等临床症状明显减轻。结论临床药师通过参与临床药物治疗,能够全面了解药物治疗面临的问题,提出合理的用药方案,这对提高药师专业水平、促进临床用药合理安全具有重要作用。

Objective To explore the effect of clinical pharmacist participating in the selection of antimicrobial agents for consultation in patients with intracranial infection. Methods 1 patient with suspected intracranial infection in September 29,2015 was admitted in our hospital.After consultation with the help of clinical pharmacist and selection of antimicrobials,the treatment drug was adjusted from cefoperazone and sulbactam to tigecycline.After treatment for 5days,the situation of patient was evaluated comprehensive.The clinical pharmacist advised to stop using tigecycline and cefazolin oxime was continuing used for down stairs treatment. Results After effective antimicrobial treatment,the inflammatory indicators liked hemogram,blood sedimentation,procalcitonin（PCT） and C-reactive protein were better than that before treatment and the clinical symptoms liked cough and expectoration were obvious alleviated. Conclusion Clinical pharmacist participating in clinical drug treatment can comprehensive understand the problem that drug treatment is facing and give reasonable treatment project,which have important role in enhancing pharmacist professional level,promoting the safety and reasonable drug use in clinical.