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重度心力衰竭的药物联合治疗效果观察

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摘要 目的观察多巴胺和硝普钠联合用药治疗重度心力衰竭的疗效。方法 20例重度心力衰竭患者,给予多巴胺和硝普钠联合治疗,比较治疗前后患者的左室舒张末期内径(LVDd)、左室射血分数(LVEF)和心搏量(SV),观察治疗效果及不良反应。结果 20例患者中显效7例(35%),有效12例(60%),总有效率为95%。与治疗前比较,患者LVDd、LVEF、SV均有改善,差异有统计学意义(P<0.05)。临床监测过程中有3例患者出现不良反应,及时减慢滴速后恢复正常。结论多巴胺和硝普钠联合用药治疗重度心力衰竭,既能降低心脏负荷,又增加心肌收缩力,使心输出量增大。必须合理调整两种药物的比例和浓度及给药速度,达到最佳血液动力学效应,改善患者心力衰竭症状,延长患者寿命。
作者 胥耀文
出处 《中国现代药物应用》 2016年第7期141-142,共2页 Chinese Journal of Modern Drug Application
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