酚妥拉明联合垂体后叶素治疗老年支气管扩张伴大咯血的疗效分析

Analysis of curative effect by phentolamine combined with pituitrin in the treatment of senile bronchiectasia complicated with massive hemoptysis

目的探究酚妥拉明联合垂体后叶素治疗老年支气管扩张伴大咯血的疗效。方法 58例老年支气管扩张伴大咯血患者,随机分为观察组和对照组,各29例。观察组给予酚妥拉明联合垂体后叶素治疗,对照组采取酚妥拉明治疗。对比两组患者的治疗效果、不良反应、总咯血量、咯血时间。结果观察组治疗总有效率96.55%高于对照组79.31%(P<0.05),两组不良反应、总咯血量和咯血时间比较,差异均有统计学意义(P<0.05)。结论老年支气管扩张伴大咯血,通过酚妥拉明联合垂体后叶素治疗,临床效果较佳,值得临床应用和推广。

Objective To investigate curative effect by phentolamine combined with pituitrin in the treatment of senile bronchiectasia complicated with massive hemoptysis. Methods A total of 58 senile patients of bronchiectasia complicated with massive hemoptysis were randomly divided into observation group and control group, with 29 cases in each group. The observation group received phentolamine combined with pituitrin for treatment, and the control group received phentolamine for treatment. Comparison was made on curative effects, adverse reactions, total hemoptysis volume, and hemoptysis time between the two groups. Results The observation group had higher total effective rate as 96.55% than 79.31% of the control group（P0.05）. The differences of adverse reactions, total hemoptysis volume, and hemoptysis time all had statistical significance between the two groups（P0.05）. Conclusion Implement of phentolamine combined with pituitrin provides excellent clinical effect in the treatment of senile bronchiectasia complicated with massive hemoptysis. It is worth clinical application and promotion.