基底动脉闭塞患者院内死亡的危险因素分析

Analysis of Risk Factors of Hospital Death in Patients with Basilar Artery Occlusion

目的探讨基底动脉闭塞(basilar artery occlusion,BAO)患者院内死亡的危险因素。方法收集2012年9月—2014年10月确诊为BAO 127例的临床资料,分为院内死亡组及生存组,对两组临床资料进行单因素及多因素logistic回归分析。结果单因素分析结果显示,院内死亡组入院时随机血糖增高、体温增高、病情严重、GCS分值低、NIHSS分值高、行气管插管或切开、肺部感染发生率高(P<0.05)。多因素logistic回归分析显示,入院时随机血糖增高、GCS评分低、NIHSS评分高、气管插管或切开为BAO院内死亡的显著危险因素(OR值分别为3.074、0.681、0.102、6.032,P<0.05)。结论入院时随机血糖增高、GCS评分低、NIHSS评分高、气管插管或切开明显增加BAO患者院内死亡的发生率。

Objective To investigate the risk factor of hospital death in patients with basilar artery occlusion（ BAO）. Methods Clinical data of 127 BAO patients confirmed during September 2012 and October 2014 were recruited in this study. They were divided into the hospital death and survival groups. The single factor and multiple factors of logistic regression analysis was performed in the two groups. Results The single factor analysis showed that hospital death group had a higher incidence rate of hyperglycemia,increasing body temperature and serious illness on admission,lower Glasgow coma score（ GCS）,higher National Institutes of Health Stroke Scale（ NIHSS） score and higher incidence rate of pulmonary infection during endotracheal intubation or incision than those in survival group（ P〈0. 05）. The multiple factors of logistic regression analysis showed that significant risk factors of hospital death were hyperglycemia on admission,low GCS and high NIHSS score and undergoing endotracheal intubation or incision（ OR = 3. 074,0. 681,0. 102 and 6. 032 respectively,P〈0. 05）. Conclusion The hyperglycemia on admission,low GCS,high NIHSS score and undergoing endotracheal intubation or incision may increase the incidence rate of hospital death.