6000例自然人群上消化道早癌内镜筛查结果分析

Endoscopic screening for early carcinoma of the upper gastrointestinal tract in 6,000 cases of natural population

目的总结分析6 000例自然人群上消化道癌早诊早治项目消化内镜筛查结果。方法采取整群抽样法,连续三年每年筛查2 000例自然人群,经内镜检查及病理活检,统计分析上消化道癌筛查结果。结果任务完成率100%,高级别上皮内瘤变及癌检出率2.03%(122例),其中高级别上皮内瘤变检出率(早诊率)为81.15%(99/122),治疗率89.8%(79/88),随访率85.71%(402/469)。男性检出率高于女性,年龄≥60岁者检出率高于其它年龄段,经统计学分析,上述差异均有显著性意义(P<0.05)。结论内镜配合病理活检能有效筛查上消化道癌;上消化道癌检出率与性别及年龄有关。

Objective To summarize and analyze the results of digestive endoscopy screening for early diagnosis and treatment of upper gastrointestinal tract cancer in 6,000 cases of natural population. Methods Two thousand cases were detected and analyzed by endoscopy and pathological biopsy via the cluster sampling method in three consecutive years. Results The completion rate was 100%. The detection rate of high-grade intraepithelial neoplasia and cancer was 2.03%（122 cases）, including 81.15%（99/122） of high-grade intraep-ithelial neoplasia. The treatment rate of high-grade intraepithelial neoplasia was 89.8%（79/88） and follow-up rate was 85.71%（402/469）. Positive rate of male was higher than female, the detection rate of persons aged 60 years or older was higher than that of other age groups, the difference was statistically significant （P〈0.05）. Conclusion Endoscopy with pathological biopsy could effectively screen the upper gastrointestinal tract can-cer. The detection rate of upper gastrointestinal tract cancer was associated with gender and age.