摘要
目的探讨Masson染色在宫颈微小浸润性鳞状细胞癌诊断中的应用价值。方法收集疑似宫颈微小浸润性鳞状细胞癌病例108例,分别对其进行Masson和免疫组化染色。结果 Masson染色和免疫组化(抗体:Ⅳ型胶原)均能清晰地显示出基底膜变薄或者缺损程度。Masson染色:70例(64.8%)为宫颈微小浸润鳞状细胞癌,20例(18.5%)宫颈原位鳞状细胞癌,18例(16.7%)为宫颈鳞状细胞癌;免疫组化染色:60例(55.6%)为宫颈微小浸润鳞状细胞癌,24例(22.2%)为宫颈原位鳞状细胞癌,24例(22.2%)为宫颈鳞状细胞癌。两者差异无统计学意义(P>0.05)。结论 Masson染色法可用来辅助诊断宫颈微小浸润鳞状细胞癌,尤其可在快速术中冰冻切片中辅助HE染色确诊有无微浸润性。
Objective To investigate the application value of Masson staining in the diagnosis of microinvasive squamous cell carcinoma of the cervix. Methods 108 cases suspected as microinvasive squamous cell carcinoma of the cervix were collected.Immunohistochemistry and Masson staining were used to detect them. Results Both Masson and immunohistochemistry staining can show basement membrane thinning or defect. Masson staining： 70（ 64. 8%） cases were microinvasive squamous cell carcinoma,20（ 18. 5%） cases were cervical carcinoma in situ,18（ 16. 7%） cases were cervical squamous cell carcinoma. Immunohistochemistry staining： 60（ 55. 6%） cases were microinvasive squamous cell carcinoma,24（ 22. 2%） cases were cervical carcinoma in situ,24（ 22. 2%） cases were cervical squamous cell carcinoma. There were no statistically difference between Masson and Immunohistochemical staining（ P〈0. 05）. Conclusion Masson staining can be used in the diagnosis of microinvasive squamous cell carcinoma of the cervix,especially in assisting HE in fast frozen.
出处
《河南医学研究》
CAS
2016年第1期17-20,共4页
Henan Medical Research
