摘要
目的评价多灶性和单发性乳头状甲状腺癌（papillary thyroid cancer,PTC）的临床病理特点的异同。方法搜集299例PTC患者,分为多灶性和单发性两组,分析多灶性和单发性PTC的临床病理特点的差别。结果多灶性PTC与单发性PTC患者在发病年龄（t=-0.017,P=0.247）,性别（χ^2=1.338,P=0.247）,肿瘤平均大小（t=-1.82,P=0.070）,伴发桥本氏炎（χ^2=2.916,P=0.088）等方面均无显著性差异,多灶性PTC比单发性PTC更易于发生淋巴结转移（χ^2=7.977,P=0.005）。各个临床病理指标上,双叶多灶性PTC与单叶多灶性PTC均无明显差异。结论多灶性可作为预测PTC淋巴结转移的指标之一。
Objective To determine the differences in clinicopathological features of multifocal and solitary papillary thyroid cancer（ PTC）. Methods The data of PTC patients was collected,and statistics was then performed to assess the differences. Results There is no significant differences in patients＇ age（ t =- 0. 017,P = 0. 247）,gender（ χ^2= 1. 338,P= 0. 247）,tumor size（ t =- 1. 82,P = 0. 070） and Hashimoto ＇s thyroiditis（ χ^2= 2. 916,P = 0. 088）. However,lymph node metastasis was significantly different between the two groups（ χ^2= 7. 977,P = 0. 005）. There were no significant difference between dual-lobe multifocal PTC and single-lobe multifocal PTC in all the clinicopathological features. Conclusion Multifocaltiy may be a predictor for the lymph node metastasis of PTC patients.
出处
《济宁医学院学报》
2016年第2期101-103,共3页
Journal of Jining Medical University
基金
济宁医学院青年基金(JYQ2011KM006)
济宁市医药卫生科技发展计划(2011-31
2015-85)
山东省高等学校科技计划(J13LK14)
山东省研究生教育创新计划项目(SDYY14014)
关键词
乳头状甲状腺癌
多灶性
临床病理特征
Papillary Thyroid Cancer
Multifocality
Clinicopathological Features
