控制患者HbA1c浓度对糖尿病并发症的影响效果研究

Research on the Influence of the Control of HbA1c Concentrations in Patients on Diabetes Complications

目的：探讨对于糖尿病患者HbA1C浓度进行控制对患者临床并发症发生的影响.方法：选取2014年1月～2015年1月在某院就诊的患有2型糖尿病患者150例,根据血液中糖化血红蛋白含量将其分成实验组和对照组.通过对两组患者进行问卷调查,统计分析临床并发症的发生情况.结果：比较两组患者的糖化血红蛋白与合并症,实验组高血压和脑血管疾病的发生率显著高于对照组（P〈0.01）,两组患者合并冠心病的发病率差异不具有统计学意义（P〉0.05）.研究糖化血红蛋白控制与并发症,实验组患有周围神经病变和脂肪肝病变并发症的发生率显著高于对照组,P〈0.05,差异具有统计学意义.结论：糖化血红蛋白的水平与糖尿病患者的常见合并症,如高血压、脑血管疾病密切相关,而且与患者的相关并发症,如周围神经病变、脂肪肝的发生具有密切关系,积极有效的控制其水平对糖尿病患者的并发症的预防具有重要意义.

Objective:To study influence of the control of HbA1 Cconcentrations on diabetes' clinical complications.Methods:Select 150 cases withtype 2diabetes treated in a hospital from January 2014 to January2015,who were randomlydivided into the experimental group and the control groupaccording to the determination of glycosylated hemoglobin content.Questionnaire survey was conducted in the two groups,then the results were compared.comparing differences between two groups of patients.Results:According to the results of the comparison between the experimental group the incidence of hypertension and cerebrovascular disease is significantly higher than control group(P<0.01),merging the incidence of coronary heart disease patients with similar between the two groups have no statistical significance(P>0.05).Study on the relationship between the control of glycosylated hemoglobin and complications,according to the results of the experimental group patients suffering from peripheral neuropathy complications and the incidence of fatty liver disease complications is significantly higher than the control group,P<0.05.Conclusion:The glycated hemoglobin level and the common complication of diabetes mellitus,closely related,such as hypertension,cerebrovascular disease,and complications associated with the patient,such as peripheral neuropathy,the occurrence of fatty liver has a close relationship,positive and effective control of its level is of great significance for the prevention of complications of diabetes mellitus.