中西医结合治疗复发性支原体感染性阴道炎临床观察

Clinical Observation of Combining Chinese and Western Medicine in the Treatment of Recurrent Mycoplasma Vaginitis

目的:观察中西医结合治疗复发性支原体感染性阴道炎的临床效果。方法:将在本院妇科进行治疗的复发性支原体感染阴道炎患者122例随机分为观察组61例和对照组61例。对照组患者用盐酸多西环素0.1g,2次/天;观察组给予盐酸多西环素的同时加服"阴道炎1号汤"加减,并用中药煎剂外洗和坐浴。两组均14天为1个疗程。分别在14天、30天后作支原体培养,评价支原体转阴率;并在治疗后2个月随访,每周1次(共连续3次),对阴道分泌物中支原体基因进行检测,比较检测结果。结果:观察组治疗14天后支原体培养转阴60例,转阴率为98.36%,治疗30天后支原体培养转阴61例,转阴率为100.00%,明显优于对照组[治疗14天后转阴50例(81.97%)、治疗30天后转阴51例(83.61%)],P<0.01;治疗60天后,观察组患者每次支原体基因检测结果和对照组每次检测结果对应比较,差异显著,P均<0.05.观察组治愈率为95.08%(58/61),对照组治愈率为81.96%(50/61),观察组的治愈率明显较高,P<0.05;对照组不良反应发生率(6.58%)明显高于观察组(0.00%),P<0.05。结论:复发性支原体感染性阴道炎采用中西医结合的方法,有协同作用,效果显著。

Objective： To analyze the clinical effect of treating recurrent mycoplasma infection vaginitis by combining Chinese and western medicine. Methods： 122 cases of recurrent mycoplasma infection in our hospital were randomly divided into observation group and controlled group,each group both had 61 cases of patients. Patients of the controlled group treated with hydrochloric acid doxycycline 0. 1g,2times daily. In the observation group hydrochloride was given doxycycline pigment at the same time,plus service ＂Vaginitis No. 1Soup＂add and subtract,and traditional Chinese medicine decoction wash and bath. Two groups were 14 days for 1courses. Respectively in 14 days,30days after mycoplasma culture,evaluation of Mycoplasma negative rate;and after treatment of 2months follow- up,1times a week（ a total of three times in a row）,on Mycoplasma gene in vaginal secretions were detected,the detection results were compared. Results： To observe the treatment group after 14 days of mycoplasma culture was negative,the negative rate was 98. 36% for 30 days after the mycoplasma culture was negative,the negative rate was100. 00%,significantly better than the controlled group（ 50 cases,81. 97%）,treated for 30 days after the negative（ 83. 61%）,P〈0. 01; the observation group patients with Mycoplasma gene detection results and each test result of the controlled group for the corresponding comparison,significant difference,P〈0. 05. The cure rate was 95. 08% and the controlled group cure rate was 81. 96%（ 50 /61）. In the observation group,the cure rate was significantly higher（ P〈0. 05）. Compared with the controlled group,the adverse reaction incidence（ 6. 58%） was significantly higher than that in the observation group（ 0. 00%）（ P〈0. 05）. Conclusion： The method of combining traditional Chinese and western medicine in recurrent mycoplasma infection vaginitis has a synergistic effect,and the effect is obvious.