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Short term effects of small incision lenticule extraction surgery on corneal endothelium

Short term effects of small incision lenticule extraction surgery on corneal endothelium
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摘要 AIM： To assess the effects of small incision lenticule extraction（SMILE） surgery on the corneal endothelium at1 d to 1mo postoperatively.·METHODS： A retrospective, observational study was conducted on 47 patients（47 eyes） who received SMILE surgery. Patients were grouped according to contact lens wear condition. The corneal endothelium was examined preoperatively and at 1d, 1wk and 1mo postoperatively.The corneal endothelium was analyzed for endothelial cell density（ECD）, percentage of hexagonal cells, and coefficient of variation（CV） of cell size.·RESULTS： There were no significant decrease in the ECD, percentage of hexagonal cells or increase in CV at1 d, 1wk and 1mo postoperatively（P 〉0.05）. However,there was a small increase of ECD by 2.88% in contact lens wearers（78.26±113.62 cell/mm2, P 〈0.05）.· CONCLUSION： SMILE has no significant adverse effects on the corneal ECD and morphology during 1mo follow-up time. AIM： To assess the effects of small incision lenticule extraction（SMILE） surgery on the corneal endothelium at1 d to 1mo postoperatively.·METHODS： A retrospective, observational study was conducted on 47 patients（47 eyes） who received SMILE surgery. Patients were grouped according to contact lens wear condition. The corneal endothelium was examined preoperatively and at 1d, 1wk and 1mo postoperatively.The corneal endothelium was analyzed for endothelial cell density（ECD）, percentage of hexagonal cells, and coefficient of variation（CV） of cell size.·RESULTS： There were no significant decrease in the ECD, percentage of hexagonal cells or increase in CV at1 d, 1wk and 1mo postoperatively（P 〉0.05）. However,there was a small increase of ECD by 2.88% in contact lens wearers（78.26±113.62 cell/mm2, P 〈0.05）.· CONCLUSION： SMILE has no significant adverse effects on the corneal ECD and morphology during 1mo follow-up time.
作者 Dan-Yang Wang Man-Li Liu Yi-Le Chen Xiao-Ying Zhang Yang-Tao Xu Jian-Chao Wang Chi-Ho To Jian-Guo Wang Quan Liu
机构地区 State Key Laboratory of Ophthalmology Department of Ophthalmology Department of Ophthalmology Laboratory of Experimental Optometry Wuzhishan Ophthalmic Hospital Hainan Eye Hospital
出处 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第4期536-539,共4页 国际眼科杂志（英文版）
基金 Supported by the National Natural Science Foundation of China(No.81261130021) Henry G Leong Endowed Professorship fund,PolyU research grant GUA32 for supporting the analysis work in Hong Kong
关键词 myopia corneal endothelium refractive surgery myopia corneal endothelium refractive surgery
分类号 R779.6 [医药卫生—眼科]
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参考文献21

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International Journal of Ophthalmology(English edition)
2016年 第4期

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