26例胎儿全前脑畸形超声诊断分析

The analysis of ultrasound diagnosis in 26 cases of fetuses with holoprosencephaly

目的：探讨产前早、中孕期超声检查对胎儿全前脑畸形的诊断价值。方法：搜集我院2011—2014年超声诊断的13～26孕周胎儿全前脑畸形病例，对其超声声像图及引产后尸检结果进行回顾性分析。结果：产前诊断13～26孕周胎儿全前脑畸形的共26例，均经引产后病理证实。结论：产前超声对胎儿全前脑畸形具有重要的诊断价值，该病特有的颅脑声像图特征和大多伴有颜面部畸形的特点，有助于诊断及鉴别诊断。

[ Objective] To explore the diagnostic value of ultrasound on fetal holoprosencephaly at first and second trimester. [ Method] The data of fetal holoprosencephaly of 13 - 26 pregnant weeks diagnosed with ultrasound in my hospital from 2011 - 2014 were collected. The ultrasonographic pictures and autopsy results post abortion were analyzed retrospectively . [ Result ]26 cases of fetal holoprosencephaly diagnosed on 13 - 26 pregnant weekswere all confirmed pathologically post abortion. [ Conclusion ] The prenatal ultrasound has important value on the diagnosis of fetal holoprosencephaly. The characteristic ultrasonographic features of brain and the features of simultaneous facial malformation contribute to diagnosis.