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同型半胱氨酸与冠心病 被引量：49

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摘要 冠心病(CHD)是由多种危险因素作用于不同环节引起的疾病,其发病率及死亡率不断上升。传统危险因素(吸烟、高脂血症、糖尿病、肥胖等)在CHD的发生过程中具有重要作用,但是它们不能完全解释CHD的发病。近年来研究发现,血浆同型半胱氨酸(Hcy)可通过多种机制促进CHD的发生,甚至有人认为高同型半胱氨酸血症是CHD的新危险因素,并且Hcy水平还可能与CHD严重程度及预后相关。补充B族维生素可以有效降低血浆Hcy水平,然而当前人们对降低Hcy水平能否预防CHD及心血管事件存在不同看法。部分研究结果提示,降低Hcy水平可预防CHD及心血管事件,然而更多研究结果并不支持这一观点,本文就Hcy与CHD关系的研究进展作一综述。
作者 张志世 王凌燕
机构地区 吉林大学中日联谊医院心血管内科
出处 《中国循环杂志》 CSCD 北大核心 2016年第4期405-407,共3页 Chinese Circulation Journal
关键词 综述 高半胱氨酸 冠状动脉疾病
分类号 R54 [医药卫生—心血管疾病]
  • 相关文献

参考文献35

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二级参考文献28

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共引文献428

同被引文献357

引证文献49

二级引证文献384

中国循环杂志
2016年 第4期

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