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血清C反应蛋白水平与进展期胃癌预后的相关性研究 被引量:2

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摘要 目的探讨C反应蛋白(CRP)与进展期胃癌临床病理学参数及预后的相关性。方法回顾性分析90例进展期胃癌患者,采用χ2检验分析血清CRP水平与进展期胃癌患者临床病理学特征的关系,单因素和多因素分析性别、年龄、肿瘤分期、CRP水平、腹腔转移、ECOG评分对预后的影响。结果血清CRP水平与患者性别、年龄、肿瘤大小、分化程度、体力状况评分无明显统计学意义,与肿瘤分期、有无腹腔转移有统计学意义(P<0.05)。单因素生存分析发现肿瘤分期、CRP水平、腹腔转移、ECOG评分与患者预后有关,而性别和年龄与预后无关。多因素生存分析发现腹腔转移和肿瘤分期是影响进展期胃癌预后的独立因素(P<0.001)。结论 CRP作为一项系统性炎症指标有助于判断患者是否存在腹腔转移,对评估患者病情及预后有指导价值。
出处 《贵州医药》 CAS 2016年第3期249-251,F0003,共4页 Guizhou Medical Journal
基金 国家自然科学基金资助项目(编号:81572329)
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参考文献12

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二级参考文献20

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