二维斑点追踪成像技术评价甲亢患者的左心室收缩功能同步性研究

Evaluation of Left Ventricular Systolic Synchronicity in Patients with Hyperthyroidism by Two Dimensional Speckle Tracking Imaging

目的:探讨二维斑点追踪成像技术在评价甲亢患者左心室收缩功能同步性的应用价值。材料与方法:对48例确诊为甲亢且常规心动图检查(ultrasonic cardiogram UCG)结果为正常的患者(简称甲亢UCG正常组),以及52例确诊为甲亢且常规心动图检查结果为异常的患者(简称甲亢UCG异常组),进行二维斑点追踪成像技术检查,计算其左心室短轴乳头肌水平前间壁及后壁心肌收缩期达峰值径向应变的时间(TRS),评价前间壁及后壁的TRS是否存在差异。同时对30例正常人进行二维斑点追踪成像技术检查。结果:甲亢UCG正常组患者的前间壁与后壁TRS比较,存在统计学差异(P<0.05);甲亢UCG异常组的前间壁与后壁的TRS比较,也存在统计学差异(P<0.05);而正常组的前间壁和后壁TRS比较,不存在统计学差异(P>0.05)。结论:与常规超声心动图比较,二维斑点追踪成像技术能较早发现并评价甲亢患者左心室收缩功能的同步性改变。

Purpose： To investigate the value of two dimensional speckle tracking imaging in evaluating systolic syn- chronicity of left ventricular in patients with hyperthyroidism. Materials arid Methods： Selected 48 patients diagnosed as hy- perthyroidism and UCG results were normal , and 52 patients diagnosed as hyperthyroidism and UCG results were abnormal. They were examined by two-dimensional speckle tracking imaging. Calculated anteroseptal and posterior wall myocardial systol- ic reached peak radial strain （TRS） from the short axis view in papillary muscle level, and analysed whether there are differ- ences between the anteroseptal and posterior wall of the TRS. Other 30 healthy people as control group. Results： The differ- ence between TRS of anteroseptal and posterior wall in the group of hyperthyroidism and UCG results were normal, was statisti- cally significant（ P 〈 0. 05 ）. The difference between TRS of anteroseptal and posterior wall in the group of hyperthyroidism and UCG results were abnormal, was also statistically significant（ P 〈 0. 05 ）. The difference between TRS of anteroseptal and pos- terior wall in the control group was not statistically significant（ P 〉 0. 05 ）. Conclusion： Compared with UCG, two dimensional speckle tracking imaging can be used to value the left ventricular systolic synchronicity in patients with hyperthyroidism. And is worthy of clinical use.