不同穿刺方法在自发性蛛网膜下腔出血患者静脉注射尼莫地平中的应用

Application of different puncture methods in the intravenous injection of nimodipine for patients with spontaneous subarachnoid hemorrhage

目的探讨不同穿刺方法在自发性蛛网膜下腔出血患者静脉注射尼莫地平中的应用效果。方法将58例自发性蛛网膜下腔出血患者分为观察组30例和对照组28例,2组均给予尼莫地平静脉注射,对照组采用浅静脉置管,观察组采用外周穿刺中心静脉置管(PICC)。观察2组导管留置时间、静脉炎发生率和患者疼痛程度。结果观察组静脉炎发生率3.33%,显著低于对照组的42.86%(P<0.01),观察组导管留置时间(13.13±4.58)d,显著长于对照组的(2.10±0.92)d(P<0.01)。观察组无痛19例、轻度疼痛9例、中度疼痛2例,对照组轻度疼痛5例、中度疼痛15例、重度疼痛8例,2组差异有统计学意义(P<0.01)。结论自发性蛛网膜下腔出血患者静脉注射尼莫地平时采用PICC置管,可延长置管时间、降低静脉炎发生率、减轻患者疼痛程度。

Objective To investigate the effect of different puncture methods in the intrave- nous injection of nimodipine for patients with spontaneous subarachnoid hemorrhage（SAH）. Methods A total of 58 SAH patients were assigned to observation group （ n = 30 ） and control group （ n = 28 ）, with intravenous injection of nimodipine for both groups. The superficial venous intubation was used in the control group and peripherally inserted central catheter （PICC） was applied in the observation group. The indwelling time of catheter, incidence of phlebitis and degree of pain were observed. Re- suits The incidence of phlebitis was 3.33% in observation group and 42.86% in control group, and the difference was significant （P 〈 0.01 ）. The observation group had a longer indwelling time com- pared with the control group [ （ 13.13 ± 4.58） d vs. （2.10 ± 0.92） d, P 〈 0.01 ]. There were 19 cases without pain, 9 cases with mild pain and 2 cases with moderate pain in observation group, and 5 cases with mild pain, 15 cases with moderate pain and 8 cases with severe pain in the control group, there was significant difference in two groups （P 〈 0.01 ）. Conclusion Injection of nimodipine and PICC for SAH patients can extend the indwelling time, reduce the incidence of phlebitis and relieve pain of patients.