口服肠溶阿司匹林缺血性脑卒中患者静脉穿刺后局部按压时间与出血情况的关系研究

Study on correlation between local pressing time and blooding after intravenous puncture in ischemic stroke patients with oral enteric aspirin

目的探讨口服肠溶阿司匹林的缺血性脑卒中患者静脉穿刺后局部按压时间与出血面积和出血率之间的关系。方法 80例缺血性脑卒中患者(静脉穿刺16次/例,共1 280例次)分成8个小组,按压时间分别为5、6、7、8、9、10、11、12 min,观察皮下出血发生率与出血面积。结果按压时间越长出血率越低,其中按压8 min与按压9min时比较,按压9 min时出血率低于按压8 min时,差异有统计学意义(P<0.01)。且按压5、6、7 min时,出血面积>2.5 cm^2发生率高于出血面积≤2.5 cm^2。按压8、9、10 min时,出血面积≤2.5 cm^2发生率高于出血面积>2.5 cm^2。结论在口服阿司匹林的缺血性脑卒中患者中,静脉穿刺时适当延长局部按压时间,能够有效预防皮下出血的发生。

Objective To explore the correlation between local compression time and bleed- ing area and bleeding rate in ischemic stroke patients with oral enteric aspirin after intravenous punc- ture. Methods A total of 80 ischemic stroke patients were divided into 8 groups. Each participant re- ceived 16 times of intravenous puncture, with a range of pressing time from 5 minutes to 12 minutes. The subcutaneous bleeding area and bleeding dence of subcutaneous bleeding was lower in rate were observed in each group. Results The inci- groups with pressing time of 9 minutes than those with pressing time of 8 minutes （P 〈 0.01 ）. In those with pressing time between 5 and 7 minutes, the inci- dence of subcutaneous bleeding was lower in participants with bleeding area~〈2.5 cm2 than those with bleeding area 〉2.5 cm2. In those with pressing time between 8 and 10 minutes, the incidence of sub- cutaneous bleeding was higher in participants with bleeding area ~〈2.5 cm2 than those with bleeding ar- ea 〉 2.5 cm2. Conclusion Prolonging pressing time after intravenous puncture appropriately can pre- vent subcutaneous bleeding in ischemic stroke patients with oral enteric aspirin.