护理干预对慢性乙肝患者抗病毒治疗依从性及生活质量的影响

Effect of nursing intervention on treatment compliance of anti- virus therapy and quality of life in patients with chronic hepatitis B

目的探讨护理干预对慢性乙型病毒性肝炎(慢性乙肝)患者抗病毒治疗依从性以及生活质量的影响。方法 96例慢性乙肝患者随机分为干预组和对照组,各48例。除对症治疗外,出院前干预组实施护理干预,主要针对患者心理、认知、用药和生活方面进行健康宣教。出院后随访3个月,对比2组患者生活质量及治疗依从性。结果出院后3个月评价生活质量,干预组在用药、生活、饮食、生理及隔离知识方面评分均显著高于对照组(P<0.01)。干预组依从率为93.75%(45/48)显著高于对照组的77.08%(37/48)(P<0.05)。结论护理干预措施能够提高慢性乙肝患者抗病毒治疗的依从性及生活质量。

Objective To investigate the effect of nursing intervention on treatment compli- ance of anti - virus therapy and quality of life in patients with chronic hepatitis B （CHB）. Methods A total of 96 CHB patients were randomly divided into intervention group （ n = 48 ） and control group （n = 48）. In addition to conventional treatment, the intervention group was given nursing inter- ventions on mental, cognition, medication and behavior of patients before discharge. The follow - up lasted for three months after discharge. The treatment compliance and quality of life were compared between two groups. Results The intervention group had higher scores in medication, behavior, diet management and knowledge of physiology and isolation compared with the controls （ P 〈 0.01 ）. The compliance rate to anti -virus therapy was 93.75% （45/48） in intervention group and was 77.08% （ 37/48 ） in control group, and a significant difference was found between the two groups （ P 〈 0.05 ）. Conclusion Nursing intervention can improve treatment compliance and quality of life in CHB pa- tients.