重症监护室患者连续性肾脏替代治疗中应用不同缓冲液的利与弊

The benefit and disadvantage between different type buffer solution continuous renal replacement therapy in critical patients in ICU

重症监护室(ICU)患者通常需行连续性肾脏替代治疗(CRRT)。CRRT过程中,不同类型的缓冲液可能对水电解质酸碱平衡及临床预后产生不同的影响。本文拟对乳酸盐、碳酸氢盐及枸橼酸缓冲液的利弊,在不同危重情形下如何选择这些缓冲液做一综述。

Critically ill patients usually require continuous renal replacement treatment（ CRRT）. Different type of buffer solution may have different influence on acid-base-electrolyte balance as well as clinical prognosis. We aimed to review the benefit and disadvantage of lactate,bicarbonate as well as citrate buffer solutions,and how to choose these buffer solutions in different critically ill patients.