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急性ST段抬高性心肌梗死合并束支传导阻滞患者红细胞分布宽度测定的临床意义 被引量:1

Prognostic Value of Red Blood Cell Distribution Width in Patients with ST- Segment Elevation Myocardial Infarction with Bundle Branch Block
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摘要 目的:研究红细胞分布宽度(RDW)在急性ST段抬高性心肌梗死(STEMI)合并束支传导阻滞(BBB)患者中的预测价值。方法随机选取STEMI合并BBB行急诊PCI术的患者117例,包括合并左束支传导阻滞(LBBB)48例和合并右束支传导阻滞(RBBB)69例的STEMI患者。根据入院24 h的首次RDW,按照其中位数将患者分成二组(RDW<12.8%和RDW≥12.8%),比较两组患者的一般资料,常规检查结果,入院时Killip分级、LVEF值、恶性心律失常、术后30 d及90 d的死亡率等指标有无差别。结果 RDW≥12.8%组患者术后1周发生恶性心律失常的比例及术后30 d及90 d的死亡率均高于RDW<12.8%组,差异具有统计学意义(P<0.05)。结论 RDW对预测合并BBB的STEMI患者预后有一定的预测价值, RDW升高的合并BBB的STEMI患者预后较差。 Objective To investigate the correlation between red blood cell distribution width (RDW) and the risk of cardiac mortality in population of patients with ST- segment elevation myocardial infarction (STEMI) with bundle branch block (BBB).Methods We studied 117 consecutive patients admitted to our hospital with STEMI with BBB confi rmed by coronary angiography from May 2011 to December 2014. Of those patients, 48 cases were left bundle branch block (LBBB) and 69 cases were right bundle branch block (RBBB). According to RDW measured immediately on admission, all patients were divided into two groups: lower group and higher group. Then we analyzed the relation between major adverse cardiovascular events and RDW. Clinical characteristics were compared between lower and higher group, then we did correlation analysis between RDW and variables that is statistically signifi cant. We also collected Killip grading of admission, LVEF values, malignant arrhythmia, the postoperative mortality in 30 days and the postoperative mortality in 90 days.Results The incidence of slow arrhythmia in patients with higher RDW group was signifi cantly greater than that in lower group, 30 and 90 days cumulative survival rate in patients with higher RDW group was signifi cantly lower than that in the lower group. Conclusion RDW was a valuable factor for predicting the prognosis of patients with STEMI. Compared with patients with lower RDW, the short-term prognosis of high level RDW with STEMI with BBB is worse.
出处 《中国血液流变学杂志》 CAS 2015年第3期297-299,352,共4页 Chinese Journal of Hemorheology
关键词 红细胞分布宽度 急性ST段抬高性心肌梗死 束支传导阻滞 预后 RDW STEMI bundle branch block prognosis
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  • 1Melgarejo-Moreno A, Galcere-Tomas J, Garcia-Alberola A, et al. Incidence, clinical characteristics, and prognostic significance of right bundle-branch block in acute myocardial infarction: a study in the thrombolytic era[J]. Circulation, 1997, 96(4): 1139-1144.
  • 2Tonelli M, Sacks F, Arnold M, et al. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease[J]. Circulation, 2008, 117(2): 163-168.
  • 3van Kimmenade RR, Mohammed AA, Uthamalingam S, et al. Red blood cell distribution width and 1-year mortality in acute heart failure[J]. Eur J Heart Fail, 2010, 12(2): 129- 136.
  • 4Sgarbossa EB, Pinski SL, Barbagelata A, et al. Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left brindle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators[J]. N Engl J Med, 1996, 334(8): 481-487.
  • 5Felker GM, Allen LA, Pocock S J, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank[J]. J Am Coil Cardiol, 2007, 50(1): 40-47.
  • 6Bansilal S, Aneja A, Mathew V, et al. Long-term cardiovascular outcoms in patients with angina pectoris presenting with bundle branch block[J]. Am J Cardiol, 2011, 107(11): 1565-1570.
  • 7Perkins SL. Examination of blood and bone marrow[M]// Greer JP, Foester J, Lukens JN, et al. Wintrobe's Clinical Hematolody. 1 lth ed. Salt Lake City, Utah: Lippincott Williams & Wilkins, 2003: 5-25.
  • 8Lippi G, Targher G, Montagnana M, et al. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients[J]. Arch Pathol Lab Med, 2009, 133(4): 628-632.
  • 9Silverberg DS, Wexler D, Blum M, et al. Erythropoietin should be part of congestive heart failure management[J]. Kidney Int Suppl, 2003, (87): $40-$47.

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