Cladosperanol A,海洋真菌Cladosporium perangustum FS62中一个新的二聚萘满酮

Cladosperanol A,a New Dimeric Tetralone from Marine-derived Fungus Cladosporium perangustum FS62

采用硅胶柱、凝胶柱、HPLC等色谱技术从海洋真菌Cladosporium perangustum FS62的发酵液提取物中分离得到了1个化合物(1),通过波谱数据分析(HR-ESI-MS、1D NMR、2D NMR、CD)确定该化合物为1个新的二聚萘满酮,结构为(4S,4'S)-4,8,8'-trihydroxy-2,3,2',3'-tetrahydro-[4',5-binaphthalene]-1,1'(4H,4'H)-dione,命名为cladosperanol A。

A new compound（ 1） was isolated from the fermentation broth extract of marine fungal strain Cladosporium perangustum FS62 by various chromatographic methods such as silica gel,reverse silica gel,Sephadex-LH20,HPLC,etc.On the basis of detailed spectroscopic analysis（ HR-ESI-MS,1D NMR,2D NMR,CD）,1 was elucidated as a new dimeric tetralone with the structure of（ 4S,4＇ S）-4,8,8（-trihydroxy-2,3,2＇,3＇- tetrahydro-[4＇,5-binaphthalene]-1,1＇（ 4H,4＇H）-dione,named as cladosperanol A.