胃左动脉栓塞术后体质量变化

Weight changes following left gastric artery embolization

目的探讨胃左动脉栓塞术对患者体质量的影响。方法回顾性分析因上消化道出血而行介入诊疗的74例患者,术中造影明确或高度可疑出血患者34例(栓塞组),对其中17例单纯采用明胶海绵颗粒行胃左动脉栓塞(观察组1),另17例采用微弹簧圈及明胶海绵颗粒行胃左动脉栓塞(观察组2);术中造影未见明确出血,未进行胃左动脉栓塞的40例患者作为对照组,分析各组患者手术前后的体质量变化情况。结果观察组1、2与对照组患者的年龄、体质量指数、恶性肿瘤病史、手术史差异均无统计学意义(P均>0.05)。与术前相比,术后3个月内观察组1患者体质量平均下降6.93%±3.98%,观察组2下降7.76%±5.37%,两组间差异无统计学意义(t=0.593,P=0.649);对照组下降2.88%±1.76%,观察组1、2与对照组比较差异均有统计学意义(t=0.254、3.179,P=0.010、0.002)。结论胃左动脉栓塞术可能导致体质量下降,有望应用于肥胖患者的治疗。

Objective To explore the changes of weight following left gastric artery（LGA）embolization.Methods A total of 74 inpatients received interventional therapy for upper gastrointestinal hemorrhage,17 inpatients underwent LGA embolization using gelfoam simply（observation group 1）,17 inpatients underwent LGA embolization using micro coils and gelfoam（observation group 2）,40 cases whose angiography were negative and no interventional treatment was performed were as the control group.The weight change in three groups was retrospectively analyzed.Results No significant difference was found in age,body mass index,malignant tumor medical history,surgery history among three groups（all P0.05）.The observation group 1,2lost an average of 6.93%±3.98%,7.76%±5.37% of their initial body weight within three months after LGA embolization,no significant differences were found between the observation group 1and 2（t=0.593,P=0.649）.The control group lost an average of 2.88%±1.76%,there were significantly differences between the observation group 1and the control group（t=0.254,P=0.010）,the observation group 2 and the control group（t=3.179,P=0.002）.Conclusion LGA embolization may lead to weight loss,which can be used in the treatment of obese patients.