EUBS-TBNA在肺癌诊断中的价值

Value of EBUS-TBNA in diagnosis of lung cancer and its complications

目的:探讨EBUS-TBNA在肺癌诊断中的价值并分析其并发症。方法:回顾性分析昆明医科大学第三附属医院2013年3月至2015年3月先行C-TBNA检查,但结果为阴性后再行EBUS-TBNA检查的171例患者的临床资料。分析EBUS-TBNA对恶性肿瘤诊断的敏感性、特异性、准确性;对恶性淋巴结的检出率和其并发症的发生率。结果:最终本研究纳入154例患者。EBUS-TBNA确诊肺癌107例,良性病变16例。31例检查阴性患者行外科手术获取最终病理诊断。并根据以上统计学数据计算出EBUS-TBNA检查对肺癌的敏感性88.42%、特异性100.00%、准确率94.21%。EBUS-TBNA共穿刺818个淋巴结,检出恶性408个,恶性检出率49.88%。1例患者出现并发症,并发症的发生率1.29%。结论:EBUS-TBNA是一种安全高效可靠的检查方法,在肺癌的诊断中有较高的价值。

Objective To investigate the value of EBUS-TBNA（endobronchial ultrasound-guided transbronchial needle aspiration） in diagnosis of lung cancer and analyze its complications.Methods A retrospective study was carried out in our hospitalfrom March 2013 to March 2015.A total of 171 patients received C-TBNA（Conventional transbronchial needle aspiration） first and got negative results.Therefore,they received EBUS-TBNA next.Weanalyzedthe sensitivity,specificity,accuracy of malignancy with EBUS-TBNA and positive（malignant） lymph node sites biopsied with EBUS-TBNAand the incidence of its complications.Results Lung cancer was proven in107 patients who had received EBUS-TBNA,while 16 were benign cases.Thirty-onenegative patients received CT guided needle biopsy or surgeryfor finally pathology.Based on above statistical data,we calculated EBUS-TBNA′s sensitivity,specificity and accuracy in 88.42%,100.00% and 94.21% respectively.A totalof 818 lymph nodes were punctured by EBUS-TBNA,408 were malignancy.The rate of diagnosis for malignancy was 49.88%.The complicationcontained 1 in hemorrhage,1 in infectionand no life-threatening conditionandno death.Conclusion The value ofdiagnosis in lung cancerisrelatively high with EBUS-TBNAin safety and efficient.