中药熏洗加四妙勇安汤联合高压氧治疗糖尿病足70例

Clinical analysis of 70 cases with diabetic foot treated with herbal fumigation and Simiao Yong’andecoction combined with hyperbaric oxygen

目的研究分析中药熏洗加四妙勇安汤联合高压氧治疗糖尿病足的临床疗效。方法选取2011年1月至2015年1月收治的糖尿病足患者210例,治疗医师根据数字表法将所有患者在常规糖尿病足治疗方法基础上随机平均分为3组,其中A组行中药熏洗加四妙勇安汤联合高压氧治疗,B组行中药熏洗加四妙勇安汤治疗,C组行高压氧治疗。治疗后观察三组患者治疗前后糖尿病足坏死创面数及跟腱反射减弱例数情况、空腹血糖、餐后2小时血糖、糖化血红蛋白、血脂指标检测、血液流变学指标变化及临床疗效评估。结果评估结果显示,A组有效率显著优于B组,差异具有统计学意义(P<0.05);B组有效率明显优于C组,差异具有统计学意义(P<0.05)。结论中药熏洗加四妙勇安汤联合高压氧治疗糖尿病足临床疗效显著,值得推广应用。

Objective To research and analysis the clinical effect of Herbal Fumigation and Simiao Yong＇an decoction combined with hyperbaric oxygen in treatment of diabetic foot. Methods 210 cases of patients with diabetic foot were chosen from January 2011 to January 2015. The patients were divided into three groups according to random number table. Group A was treated with herbal Fumigation and Simiao Yong＇an decoction combined with hyperbaric oxygen,group B was treated with herbal Fumigation and Simiao Yong＇an decoction and group C was treated with hyperbaric oxygen. After treatment,the number of diabetic foot necrosis wound and Achilles tendon reflex weakened patients were recorded,fasting blood glucose,postprandial 2 hours blood glucose,glycosylated hemoglobin,blood lipids,blood rheology index changes and clinical efficacy evaluation were observed. Result The results showed that the efficiency of A group was significantly better than that of B group,the difference was statistically significant（ P〈0. 05）;the efficiency of B group was significantly higher than that in C group,the difference was statistically significant（ P〈0. 05）. Conclusion Herbal fumigation and Simiao Yong＇an decoction combined with hyperbaric oxygen in treatment of diabetic foot have a better clinical curative effect,and it is worth widely used in clinic.