完整切除并予抗结核药物治疗婴幼儿卡介苗性淋巴结结核的预后研究

The prognosis of complete resection combined with anti tuberculosis drugs in the treatment of infantile BCG lymph node tuberculosis

目的研究婴幼儿卡介苗性淋巴结结核完整切除术后抗结核药物应用与预后的关系。方法分析133例卡介苗性淋巴结结核完整切除术后患儿回访资料,按照服抗结核药物情况分为3组,对照组46例未服用抗结核药物;服药Ⅰ组36例,同时服用异烟肼和利福平3个月后停药;服药Ⅱ组51例,同时服用异烟肼和利福平3个月改为单服异烟肼3个月后停药。结果对照组复发1例(2.17%),服药Ⅰ组复发2例(5.56%),服药Ⅱ组复发1例(1.96%),复发病例与服抗结核药物之间比较差异无统计学意义(P>0.05)。结论卡介苗性淋巴结结核的预后与抗结核药物应用无关,其预后主要取决于是否完整切除病灶。

Objective To study the relationship between the application of anti tuberculosis drug and the prognosis after complete resection of the infant BCG lymph node tuberculosis. Methods Analyze the follow- up dates of 133 cases whose BCG lymph node tuberculosis have been completely resected. According to the anti- TB drugs taking,the patients were randomly divided into 3 groups.The control group did not take the anti- tuberculosis drugs. Administered group I took both isoniazid and rifampicin for 3 months. Administered group II took isoniazid for 3 months after taking both isoniazid and rifampicin for 3 months. Results In the control group,there was 1 case with recurrence（ 2. 17%）. In administered group I,2 cases relapsed（ 5. 56%）. In administered group II,1 case relapsed（ 1. 96%）. There were no statistical differences between them（ P〉0. 05）. Conclusions The application of anti- TB drugs has nothing to do with the prognosis. The prognosis mainly depends on whether the nidus was completely resected or not.