步行运动对左心室射血分数保留心力衰竭患者的运动耐力的影响

Influence of walk exercise on exercise tolerance in patients with heart failure with preserved left ventricular ejection fraction

目的观察在药物治疗基础上步行运动训练对左心室射血分数保留心力衰竭(HFPEF)患者心功能康复的效果。方法 142例HFPEF患者在药物治疗基础上分为两组;对照组70例,只给予常规药物治疗,但无运动处方;运动组72例,按设定的运动处方进行康复训练。经过24周的随访,比较两组6min步行试验距离、血浆N末端前脑钠肽(NT-proBNP)和左心室舒张功能等指标变化。结果运动组与运动训练前及对照组比较6 min步行试验距离、静息心率显著增加、NT-proBNP显著降低(P<0.01)。结论按运动处方进行步行训练能显著改善HFPEF患者的运动耐力。

Objective To evaluate the rehabilitation effects of walk exercise training on the heart function rehabilitation in the patients with heart failure with preserved left ventricular ejection fraction（HFPEF）.Methods A total of 142 cases of HFPEF were randomly assigned to 2groups on the basis of medication therapy;the control group（70cases）was given only routine medication therapy without the exercise prescription;On the bases of control group,the exercise group（72cases）conducted the rehabilitation training according to the exercise prescription.After 24 weeks follow up,6min walking distance,plasma NT-proBNP level and left ventricular diastolic function were compared between the two groups.Results The 6min walking distance after walk exercise training in the exercise group was significantly increased compared with before walk exercise training and the control group,while the level of NT-proBNP was significant decreased（P〈0.01）.Conclusion The walking exercise training mode according to the exercise prescription can significantly improve the exercise tolerance in the HFPEF.